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August 18, 2025Open Access

Figure S4 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

Eshwari Dathathri Fikri Abali Michiel Stevens Richell Booijink Tanja C. van Dijk Khrystany T. Isebia John W.M. Martens Jaco Kraan Nick Beije Martijn P. Lolkema Peter A.W. te Boekhorst Paul Hamberg Brigitte C.M. Haberkorn Danny Houtsma Joan van den Bosch Wendy M. van der Deure Ruchi Bansal Leon W.M.M. Terstappen

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Key Points

PSA levels were accurately measured from single circulating tumor cells, highlighting precision in detection.
The calibration demonstrated a strong correlation with R2 = 0.97, affirming the method’s reliability in measuring PSA.
The approach involved serial dilutions of PSA proteins analyzed for intensity on PVDF membranes, ensuring a precise quantification technique.
These findings underscore the importance of accurate PSA measurement in metastatic prostate cancer, aiding in clinical decision-making.

Implication

Calibration graph shows PSA levels from circulating tumor cells in prostate cancer, indicating measurement reliability.

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Cite This Study

Dathathri et al. (2025) studied this question.

synapsesocial.com/papers/68af4328ad7bf08b1ead2249 https://doi.org/10.1158/2767-9764.29929858

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure 5 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients2025
2Figure S6 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients2025
3Figure S5 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients2025
4Figure S1 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients2025
5Figure 6 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients2025