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August 19, 2025BMC GastroenterologyOpen Access

Association between gastrointestinal disorders and sleep-related problems: the mediating effect of depression

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Authors

SYShicheng YeSLSui LiliXZXuan Zeng

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Overview

Observational analysis reveals significant links between gastrointestinal disorders and sleep issues, suggesting depression's mediating role.

Key Points

  • Individuals with gastrointestinal diseases showed a 70% higher risk of experiencing sleep troubles, indicating significant associations.
  • Gastrointestinal disorders increased the odds of sleep disorders with a 80% elevated probability, emphasizing severe sleep disruptions.
  • Mediation analysis demonstrated that depression partially mediates sleep trouble, sleep disorders, and sleep duration, highlighting psychological impacts.
  • These findings call for comprehensive clinical strategies that integrate management of gastrointestinal and mental health to enhance sleep quality.

Cite This Study

Ye et al. (2025) studied this question.

synapsesocial.com/papers/68af4953ad7bf08b1ead4ec9https://doi.org/10.1186/s12876-025-04180-8
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