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October 10, 2025JGH OpenOpen Access

Association Between Digestive Diseases, Nighttime Sleep, and Depressive Symptoms Among the Middle‐Aged and Elderly Adults: A Mediation Analysis

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Authors

CCChaoze ChengDGDeliang GuoXCXu Cao

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Overview

Mediation analysis reveals the link between digestive diseases and depressive symptoms in middle-aged and elderly adults, suggesting sleep's crucial role.

Key Points

  • Insufficient nighttime sleep partially mediates the relationship between digestive diseases and depressive symptoms.
  • The prevalence of digestive diseases is 23.05%, with depressive symptoms detected at 35.90%.
  • Multivariate logistic regression shows significant associations between digestive diseases and depressive symptoms.
  • Findings underscore the importance of addressing nighttime sleep quality in managing depression among patients with digestive diseases.

Cite This Study

Cheng et al. (2025) studied this question.

synapsesocial.com/papers/68e861857ef2f04ca37e3be6https://doi.org/10.1002/jgh3.70294
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The association between nighttime sleep duration and digestive diseases in middle-aged and older population in China: mediating role of depression2026
  2. 2Association between gastrointestinal diseases and depression severity among middle-aged and older Chinese women: the mediating effect of sleep duration2026
  3. 3Associations of sleep duration variability and depressive symptoms with gastrointestinal disease among middle-aged and older adults2026
  4. 4Association between gastrointestinal disorders and sleep-related problems: the mediating effect of depression2025
  5. 5Joint associations of sleep quality and depressive symptoms with incident digestive disease in a nationally representative Chinese cohort2026