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August 19, 2025PLoS ONEOpen Access

Randomized controlled trial of stress management and resiliency training for depression (SMART-D)-pilot study

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Authors

ASAshok SeshadriMFMatthew Fuller‐TyszkiewiczLHLaura Harper

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Overview

Randomized controlled trial improved depression and stress in adults with MDD receiving standard treatments, suggesting adjunctive support is beneficial.

Key Points

  • Adjunctive resiliency training reduced depression scores significantly compared to standard treatment alone, highlighting its potential benefits.
  • Participants in the SMART-D group experienced a notable decrease in stress levels after 3 months, with a significant group-time interaction observed.
  • This pilot RCT assessed 27 adults with MDD, providing initial insights into the advantages of stress management interventions in enhancing treatment outcomes.
  • Further research with larger samples is necessary to solidify the findings, as the small participant size limits definitive conclusions.

Cite This Study

Seshadri et al. (2025) studied this question.

synapsesocial.com/papers/68af4953ad7bf08b1ead4f8ahttps://doi.org/10.1371/journal.pone.0328539
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