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Introducing the New Definition and Diagnostic Criteria of Disseminated Intravascular Coagulation Released by the International Society on Thrombosis and Haemostasis in 2025

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Updated definitions improve diagnosis of disseminated intravascular coagulation in clinical settings, highlighting sepsis and thrombotic DIC.

The revised criteria for disseminated intravascular coagulation enable earlier diagnosis and management, facilitating better patient outcomes.
Key indicators for DIC include platelet count, prothrombin time, international normalized ratio, and fibrinogen levels, guiding treatment.
The new phase-based classification distinguishes between pre-DIC, early-phase DIC, and overt DIC, enhancing diagnostic clarity.
Updated criteria categorize DIC into thrombotic and hemorrhagic phenotypes, addressing the condition's diverse manifestations.

Iba et al. (2025) studied this question.

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Updated definitions improve diagnosis of disseminated intravascular coagulation in clinical settings, highlighting sepsis and thrombotic DIC.