Comparative study shows longer sildenafil use reduces pulmonary hypertension in mitral valve surgery patients, suggesting improved outcomes.
Key Points
Reduction in mean pulmonary artery pressure was greater in the long course group, achieving a drop of 24.83±5.04mmHg compared to 16.46±4.13mmHg in the short course group.
Statistical analysis revealed significant differences in postoperative pressures, with a p-value less than 0.05, indicating stronger effects of longer sildenafil use.
The study involved patients from King Edward Medical University over a period from July 2024 to January 2025, aiming to assess perioperative pulmonary outcomes.
Longer administration of sildenafil has been validated in managing pulmonary hypertension related to mitral valve surgery.