⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

August 15, 2025Open Access

Figure S5 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer

Daniela Conticelli Marco Volante Filippo Pietrantonio Claudia Orrù Martina Olivero Alessia Nottegar Felice Borghi Gian Luca Baiocchi Giovanni Crotti Uberto Fumagalli Romario Giovanni De Manzoni Rossella Reddavid Roberta Porporato Dinçer Kılıç Rebecca Ghione Erika Calabrò Russell Petty Simona Corso Silvia Giordano Cristina Migliore

View Full Paper

Ask AI

Bookmark

Share

Key Points

Cetuximab sensitivity correlates with EGFR and HER2 expression in cells, indicating predictive biomarkers for treatment outcomes.
Evaluation of cell lines revealed distinct levels of EGFR and HER2, highlighting their role in therapy response.
Analysis focused on sensitive versus resistant cells to determine the impact of biomarkers in treatment success.
Identifying biomarkers can enhance targeted therapies in gastroesophageal cancer, potentially improving patient outcomes.

Implication

Evaluation shows cetuximab sensitivity linked to EGFR and HER2 levels in gastroesophageal cancer cells, suggesting biomarkers for treatment.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Conticelli et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd12e https://doi.org/10.1158/0008-5472.29918894

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S3 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
2Figure S10 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
3Figure S2 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
4Figure S8 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
5Figure S7 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025

More related papers

Figure S9 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
Figure S6 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
Figure S1 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025