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August 15, 2025

Figure S10 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer

Daniela Conticelli Marco Volante Filippo Pietrantonio Claudia Orrù Martina Olivero Alessia Nottegar Felice Borghi Gian Luca Baiocchi Giovanni Crotti Uberto Fumagalli Romario Giovanni De Manzoni Rossella Reddavid Roberta Porporato Dinçer Kılıç Rebecca Ghione Erika Calabrò Russell Petty Simona Corso Silvia Giordano Cristina Migliore

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Key Points

EGFR pathway activation predicts treatment response in gastroesophageal cancer, emphasizing its role as a biomarker.
Key evidence shows that the presence of specific biomarkers can indicate the effectiveness of EGFR inhibition in treatment.
Assessment of biomarkers involves examining EGFR activation pathways and their correlation with patient responses to treatment.
These findings suggest the potential for personalized treatment approaches based on biomarker evaluations in gastroesophageal cancer.

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Implication

Evaluation highlights EGFR and biomarkers linked to treatment response in gastroesophageal cancer.

Abstract

Evaluation of EGFR pathway activation.

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Cite This Study

Conticelli et al. (2025) studied this question.

synapsesocial.com/papers/68af5bafad7bf08b1eadf345 https://doi.org/10.1158/0008-5472.29918909

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Figure S9 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
2Figure S5 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
3Figure S2 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
4Figure S6 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
5Figure S1 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025

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Figure S8 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025
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Figure S3 from AREG and EREG Are Predictive Biomarkers of Response to EGFR Inhibition in Gastroesophageal Cancer2025