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September 5, 2025CancersOpen Access

Modern Approaches to Rectal Cancer: Integrating Endoscopic, Surgical, and Oncological Care

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Authors

JKJiří KotekJCJiří CyranyMSMiroslav Sirový

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Overview

This review demonstrates improved outcomes of neoadjuvant therapy and endoscopic treatment in rectal cancer, suggesting a tailored approach for better results.

Key Points

  • Neoadjuvant chemoradiotherapy enhances resectability and improves local control for advanced tumors.
  • Endoscopic treatment provides less invasive, organ-preserving options for selected early-stage rectal cancers.
  • Surgical resection through total mesorectal excision remains the key curative strategy in rectal cancer treatment.
  • Advanced procedures such as pelvic exenteration may offer cure potential in recurrent cases despite higher morbidity.

Cite This Study

Kotek et al. (2025) studied this question.

synapsesocial.com/papers/68bb3d682b87ece8dc956bcbhttps://doi.org/10.3390/cancers17172820
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A modern approach to rectal cancer2026
  2. 2Organ preservation in rectal cancer: an endoscopist’s perspective on current evidence and future directions2026 · 1 citations
  3. 3Neoadjuvant Treatment for Locally Advanced Rectal Cancer: Current Status and Future Directions2025
  4. 4Therapeutic Advances in Rectal Cancer2025
  5. 5Advancing Personalized Medicine in the Treatment of Locally Advanced Rectal Cancer2024 · 3 citations