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September 5, 2025Open Access

Supplementary Figure S6 from RORγt Inhibition Reduces Protumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer

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RORγt inhibition reduces tumor growth in lung cancer, suggesting potential for inflammation management.

RORγt inhibition decreased tumor growth significantly in experimental models of lung cancer.
The analysis shows that Rorg expression does not increase in LLC CSCs, indicating stability in these cancer stem cells.
Observational analysis in multiple lung cancer models suggests a link between inflammation reduction and tumor size decrease.
This finding highlights the potential importance of targeting RORγt for cancer treatment strategies.

Yamada‐Hara et al. (2025) studied this question.

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