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September 5, 2025Open Access

Supplementary Figure S7 from RORγt Inhibition Reduces Protumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer

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Inhibition of RORγt reduces tumor growth and inflammation in lung cancer models, indicating a potential therapeutic target.

RORγt inhibition decreases tumor growth in experimental lung cancer models, showing its potential as a therapeutic target.
Expression levels of Rorg were not increased in cancer stem cells isolated from KrasG12D mouse lungs, highlighting differing mechanisms.
The findings are based on experimental models, supporting the role of inflammation in tumor progression.
The results suggest that targeting RORγt may be effective in managing protumor inflammation and lung cancer growth.

Yamada‐Hara et al. (2025) studied this question.

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