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September 5, 2025MedicineOpen Access

Association between triglyceride–glucose index and all-cause and cardiovascular mortality in US adults: A cohort study

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Authors

CYChen Yan YueDHDong HuiHLHailun Liu

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Overview

Cohort study examines the link between triglyceride-glucose index and mortality rates in adults, highlighting significant associations.

Key Points

  • Elevated triglyceride-glucose index values significantly increase all-cause and cardiovascular mortality rates among adults, particularly those aged 40 to 60.
  • Kaplan–Meier curves revealed pronounced differences in mortality rates across quartiles, indicating the relevance of triglyceride-glucose index levels.
  • Cox regression models and restricted cubic splines were employed to analyze the association between the triglyceride-glucose index and mortality over nearly two decades.
  • The findings underscore the importance of monitoring triglyceride-glucose index as a risk factor for mortality in middle-aged adults.

Cite This Study

Yue et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f7a6d6d5674bcd03ca3https://doi.org/10.1097/md.0000000000043897
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association between Triglyceride-Glucose Index and risk of all-cause and cardiovascular mortality in adults with prior cardiovascular disease: a cohort study using data from the US National Health and Nutrition Examination Survey, 2007–20182024 · 11 citations
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  3. 3Nonlinear Relationship Between the Triglyceride–Glucose Index and All‐Cause and Cardiovascular Mortality in Diabetes Mellitus Patients With Hypertension: A National Cohort Study2026
  4. 4Association of the triglyceride-glucose index with all-cause and cardiovascular mortality in patients with cardiometabolic syndrome: a national cohort study2024 · 83 citations
  5. 5Nonlinear relationship between triglyceride-glucose index and cardiovascular mortality with competing risk analysis on populations aged 18–80 years2025 · 2 citations