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September 5, 2025MedicineOpen Access

Exploring the relationship between metabolic syndrome and vestibular dysfunction: NHANES data and Mendelian randomization analysis

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Authors

LZLingli ZhangSLShihan LiuYLYifan Li

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Overview

Analysis reveals no significant causal link between metabolic syndrome and vestibular dysfunction, suggesting hypertension and cholesterol could be risk factors.

Key Points

  • The study found no strong causal relationship between metabolic syndrome and vestibular dysfunction, despite some correlations.
  • NHANES data analysis revealed a correlation, which diminished after adjusting for sociodemographic factors.
  • Mendelian randomization analysis did not support a significant causal link, but identified hypertension and low HDL cholesterol as vestibular risks.
  • Findings indicate components of metabolic syndrome may independently contribute to vestibular dysfunction risk and suggest targets for prevention.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68bb5f7a6d6d5674bcd03cc2https://doi.org/10.1097/md.0000000000044097
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exploring the relationship between Metabolic Syndrome and Vestibular Dysfunction: insights from NHANES data and mendelian randomization analysis2024
  2. 2Causal association between blood metabolites and vertigo: A Mendelian randomization study2024 · 1 citations
  3. 3Causality of the Metabolic Syndrome and its Ingredients on Cardiovascular Disease: A Two-sample Mendelian Randomization Analysis2026
  4. 4The association of metabolic syndrome with aortic aneurysm: a two-sample Mendelian randomization study2025
  5. 5Causal Relationship Between Hypertension And Vertigo: A Mendelian Randomization Study2025