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September 10, 2025Open Access

Figure S13 from Intrinsic Properties of the Lymph Node Render It Immunologically Susceptible to Metastasis

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Transient depletion of Tregs successfully prevents metastasis in lymph nodes, indicating a critical immune role.
Key evidence includes the observation that depleted Treg levels correlate with reduced metastasis rates.
The approach utilized involved analyzing immune responses following local depletion of Tregs in lymph nodes.
These findings highlight potential therapeutic strategies targeting immune vulnerabilities in cancer metastasis.

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Analysis shows Treg depletion prevents metastasis in lymph nodes, suggesting immunological vulnerabilities.

Transient, local depletion of Tregs in the tdLN prevents metastasis

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Kahn et al. (2025) studied this question.

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Analysis shows Treg depletion prevents metastasis in lymph nodes, suggesting immunological vulnerabilities.

Transient, local depletion of Tregs in the tdLN prevents metastasis