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September 4, 2025Open Access

Table S3 from Intrinsic Properties of the Lymph Node Render It Immunologically Susceptible to Metastasis

Benjamin Kahn Raymond W.S. Ng Il‐Kyu Kim Cody Eskandarian Chelsey Chen Bing Huang Alfredo Lucas Lequn Li Ivan Maillard Ben Z. Stanger

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Key Points

Tregs provide a significant protective advantage for OVA+ tumor cells when injected into lymph nodes, enhancing their survival.
The study highlights the role of the lymph node environment in fostering susceptibility to metastasis via Tregs.
Injected OVA+ tumor cells experience a protective effect from Tregs, suggesting Tregs might facilitate tumor spread.
This research illuminates the immunological dynamics in lymph nodes, emphasizing Tregs' influence on metastasis in tumors.

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Implication

Observation shows Tregs provide a protective advantage to OVA+ tumor cells in lymph nodes, indicating a role in metastasis.

Abstract

Tregs confer protective advantage to OVA+ tumor cells after intra-LN injection

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Cite This Study

Kahn et al. (2025) studied this question.

synapsesocial.com/papers/68c18c109b7b07f3a0614bff https://doi.org/10.1158/2159-8290.30050758

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