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September 10, 2025Aesthetic Cosmetology and Medicine

Clinical evaluation of the effect of non-crosslinked hyaluronic acid injections on skin parameters with signs of aging. Case study

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Authors

AKAdrian KaramonIBIzabela Błażewicz

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Overview

Case study evaluates hydration and elasticity improvements from hyaluronic acid in aging skin.

Key Points

  • Injections of hyaluronic acid improved skin hydration and firmness in aging skin, with lasting effects.
  • Skin thickness and density increased after treatment with non-crosslinked hyaluronic acid preparations.
  • Four women aged 35-46 received injections, showing significant improvements one month post-treatment.
  • The therapy enhanced natural regenerative processes, indicating skin health benefits.

Cite This Study

Karamon et al. (2025) studied this question.

synapsesocial.com/papers/68c195559b7b07f3a061902dhttps://doi.org/10.52336/acm.2025.022
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Morphometric analysis of the effects of high molecular weight sodium hyaluronate and amino acids mixture on face rejuvenation2024 · 5 citations
  2. 2Efficacy and Safety of Non-cross-Linked Hyaluronic Acid Injections for Facial Skin Biorevitalization: A Single-Center, Open-Label, Single-Arm, Uncontrolled, Post-marketing Study2025 · 6 citations
  3. 3The efficacy of hyaluronic acid fragments with amino acid in combating facial skin aging: an ultrasound and histological study2024 · 6 citations
  4. 4Morphological and immunohistochemical characteristics of skin specimens after isolated and combined injections of poly-L-lactic acid and hyaluronic acid2025
  5. 5Safety and Efficacy of an Injectable Solution Enriched With Sodium Hyaluronate, Amino Acids, and Peptides in Relation to Superficial Facial Connective Tissues (Dermis and Retinacular Cutis)2024 · 2 citations