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September 10, 2025Journal of International Medical ResearchOpen Access

Outcomes of overweight and obese critically ill patients with severe acute respiratory infection

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Authors

AAAbdurahman Najy AyoupKing Saud bin Abdulaziz University for Health SciencesHTHaytham TlayjehKing Saud bin Abdulaziz University for Health SciencesJJJesna JoseKing Saud bin Abdulaziz University for Health Sciences

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Implication

Retrospective cohort study shows lower mortality in obese patients with severe acute respiratory infection, suggesting an obesity paradox.

Key Points

  • Overweight-obese patients had lower 90-day mortality than normal-weight patients, supporting the obesity paradox.
  • Multivariate regression indicated a mortality odds ratio of 0.71 for overweight-obese patients, with significant associations from age and Sequential Organ Failure Assessment score.
  • A total of 421 patients were analyzed, with 294 in the overweight-obese group and 127 in the normal-weight group, revealing interesting findings on obesity and health outcomes.
  • Increasing age and Sequential Organ Failure Assessment scores were linked to higher mortality rates, implying important considerations for management in critically ill patients.

Cite This Study

Ayoup et al. (2025) studied this question.

synapsesocial.com/papers/68c198ab9b7b07f3a0619d76https://doi.org/10.1177/03000605251370302
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