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September 10, 2025Anti-Cancer Agents in Medicinal Chemistry

The Promising Role of PKM2 in the Diagnosis and Prognosis of Ovarian Cancer

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Authors

PBP BorraUlsan CollegePCPhool ChandraTeerthanker Mahaveer UniversityHSHimanshu SharmaTeerthanker Mahaveer University

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Overview

Research demonstrates PKM2's potential as a diagnostic biomarker in ovarian cancer, suggesting novel therapeutic approaches.

Key Points

  • PKM2 improves diagnostic accuracy and offers new therapeutic strategies in ovarian cancer.
  • High fatality rates and late-stage diagnosis make early detection critical for better outcomes.
  • The role of PKM2 in cancer metabolism, including the warburg effect, reinforces its therapeutic significance.
  • Rigorous validation is necessary to incorporate PKM2-based treatments into clinical practice.

Cite This Study

Borra et al. (2025) studied this question.

synapsesocial.com/papers/68c198cd9b7b07f3a061adefhttps://doi.org/10.2174/0118715206394408250806065235
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Also Consider

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  4. 4Prognostic Value of PKM2 Expression in de novo Metastatic Colorectal Cancer Patients2025 · 1 citations
  5. 5Pyruvate Kinase M2: Function, Regulation and Targeting Therapeutics In Cancer2026