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September 10, 2025PLoS ONEOpen Access

Association of serum lysophosphatidylcholine acyltransferase 3 levels with metabolic variables and risk of type 2 diabetes mellitus: A cross-sectional study

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Authors

HZHaifeng ZhuZZZiyi ZhongJJJing Jin

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Overview

Cross-sectional study found lower LPCAT3 in T2DM patients, indicating its complex link to obesity and metabolic variables.

Key Points

  • Serum LPCAT3 levels were lower in type 2 diabetes mellitus patients compared to individuals with normal glucose tolerance.
  • Negative correlations were found between LPCAT3, body mass index, and high-density lipoprotein cholesterol in T2DM patients.
  • Linear regression indicated that body mass index, high-density lipoprotein cholesterol, and fasting blood glucose are predictors of LPCAT3 levels.
  • Predictive value of LPCAT3 for type 2 diabetes mellitus remains limited due to confounding by obesity-related factors.

Cite This Study

Zhu et al. (2025) studied this question.

synapsesocial.com/papers/68c19f9c54b1d3bfb60db440https://doi.org/10.1371/journal.pone.0329301
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Also Consider

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