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September 10, 2025Letters in Applied Microbiology

Protective effects of novel probiotic strains against LPS-induced inflammation in RAW264.7 macrophages

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Authors

ASAkanksha SinghPNPradeep Singh Negi

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Overview

This analysis reveals novel probiotic strains that reduce LPS-induced inflammation, suggesting potential gut-targeted therapies.

Key Points

  • Both Lactiplantibacillus plantarum CRT01 and Levilactobacillus brevis CAB20 significantly reduce LPS-induced inflammatory markers.
  • These strains demonstrate impressive antioxidant activity and modulate key cytokines like TNF-α and IL-10.
  • The in vitro assessment utilized RAW 264.7 macrophages to evaluate immune modulation and antioxidant capacity.
  • This research suggests promising applications of plant-based probiotics in managing inflammation and oxidative stress.

Cite This Study

Singh et al. (2025) studied this question.

synapsesocial.com/papers/68c1a78154b1d3bfb60e1032https://doi.org/10.1093/lambio/ovaf104
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