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September 10, 2025Journal of Applied Polymer Science

Bio‐Responsive Hyaluronic Acid‐Stearylamine Copolymer as an Enzyme Responsive Drug Carrier System: Intelligent Fusidic Acid Loaded Nanomicelles for Potential Treatment of Bacterial Wound Infections

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Authors

NUNoor UllahARAsim Ur RehmanPGParsa Gul

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Overview

This research demonstrates enzymatic degradation of a hyaluronic acid-copolymer in nanomicelles, suggesting improved drug delivery for bacterial infections.

Key Points

  • Fusidic acid nanomicelles exhibit high encapsulation efficiency of 87%, enhancing delivery methods.
  • The bio-responsive copolymer degrades in the presence of Staphylococcus aureus, enabling targeted drug release.
  • Characterization revealed the copolymer's successful synthesis through spectral analysis and thermal behavior studies.
  • This enzyme-triggered strategy may improve treatment outcomes for bacterial infections while minimizing side effects.

Cite This Study

Ullah et al. (2025) studied this question.

synapsesocial.com/papers/68c1ad5c54b1d3bfb60e555ahttps://doi.org/10.1002/app.57771
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