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September 10, 2025International Journal of Medical and All Body Health Research

Hypotension after General Anesthesia Induction with Remimazolam or Propofol in Geriatric Patients Undergoing Sevoflurane Anesthesia with Remifentanil

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Authors

ABAbhi Sarika BhartiKJKeshav Dev JagarSSShailja Sharma

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Overview

Prospective, randomized trial shows lower hypotension rates with remimazolam in elderly patients, suggesting improved hemodynamic stability during anesthesia.

Key Points

  • Remimazolam significantly reduced hypotension incidence compared to propofol in elderly patients during anesthesia induction.
  • The incidence of hypotension was 32.2% in the remimazolam group versus 57.8% in the propofol group (p<0.001).
  • A prospective, randomized, double-blind study involved 180 patients aged ≥65 years undergoing elective surgery.
  • Remimazolam demonstrated superior hemodynamic stability, reducing vasopressor requirements by 40% compared to propofol.

Cite This Study

Bharti et al. (2025) studied this question.

synapsesocial.com/papers/68c1b35454b1d3bfb60e9d31https://doi.org/10.54660/ijmbhr.2025.6.3.186-192
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hypotension after general anesthesia induction using remimazolam in geriatric patients: Protocol for a double-blind randomized controlled trial2022 · 19 citations
  2. 2Comparison of Remimazolam and Propofol on Post-Induction Hypotension in Elderly Hypertensive Patients: A Randomized Controlled Trial2025 · 8 citations
  3. 3Comparison of hemodynamics during induction of general anesthesia with remimazolam and target-controlled propofol in middle-aged and elderly patients: a single-center, randomized, controlled trial2023 · 39 citations
  4. 4Comparison of hemodynamics during induction of general anesthesia with remimazolam and target-controlled propofol in middle-aged and elderly patients: A single-center, randomized, controlled trial2022 · 5 citations
  5. 5Effect of remimazolam vs. propofol on hemodynamics during general anesthesia induction in elderly patients: Single-center, randomized controlled trial2023 · 16 citations