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September 10, 2025Materials Today BioOpen Access

Nanofibrous Dressings Modified with Antibacterial Polylysine and Anti-inflammatory Tannic Acid for Infected Wound Healing

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Authors

WXWei XuTXTingting XuLYLei Yu

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Overview

Novel nanofibrous dressings demonstrate reduced bacterial burden and enhanced healing in infected wounds, indicating antibacterial and anti-inflammatory potential.

Key Points

  • PLys@TA@PLCL nanofibers significantly reduced bacterial burden and accelerated healing in infected wounds.
  • In vitro studies showed these dressings significantly suppressed inflammatory responses and enhanced ECM deposition.
  • PLys@TA@PLCL dressings demonstrated robust anti-inflammatory activity, leading to nearly complete wound closure within 2 weeks.
  • The synergistic effects of polylysine and tannic acid highlight the utility of these dressings in chronic wound management.

Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68c1b60d54b1d3bfb60eb310https://doi.org/10.1016/j.mtbio.2025.102155
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