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September 10, 2025International Journal of Scientific Research

Effect of LNG Iucd (Mirena) vs Dienogest in Adenomyosis: A Randomized Control Trial

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Authors

MJMeenakshi JohariSKSwati KumariPatna Medical College and HospitalHPHiren PatelNational Institute for Research in Reproductive Health

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Implication

Randomized controlled trial finds dienogest better for symptom control in adenomyosis, while LNG-IUS reduces uterine volume.

Key Points

  • Dienogest provides superior reduction in pain and menstrual volume at 6 and 12 months.
  • LNG-IUS effectively reduces uterine volume, though it has higher rates of irregular bleeding.
  • Randomized controlled trial with 100 women diagnosed with adenomyosis compared both treatments.
  • Dienogest offers better long-term symptom control and is a favorable option for treatment.

Cite This Study

Johari et al. (2025) studied this question.

synapsesocial.com/papers/68c1b81254b1d3bfb60ebea2https://doi.org/10.36106/ijsr/1003573
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of levonorgestrel releasing intrauterine system in the treatment of symptomatic adenomyosis: comparison with dienogest2025
  2. 2Comparison of the effects of levonorgestrel‐releasing intrauterine system and dienogest treatment on systemic inflammatory markers ( NLR , PLR , SII ) and anemia parameters in patients with adenomyosis at 6 months2026
  3. 3Fertility outcome following ovarian stimulation in infertile women having pretreatment with levonorgestrel releasing intrauterine system versus dienogest for symptomatic adenomyosis2025
  4. 4Clinical Efficacy of Dienogest for Symptomatic Adenomyosis2026
  5. 5Laparoscopic adenomyomectomy combined with l evonorgestrel‐releasing intrauterine system in the treatment of adenomyosis: Feasibility and effectiveness2020 · 12 citations