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September 10, 2025GSC Advanced Research and Reviews

From early growth failure to endocrine recovery: Long-term outcomes and GH therapy in SGA and severely preterm children

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Authors

ASAshraf SolimanHAHaytham AliHAHamdy Ali

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Overview

Mini-review evaluates efficacy of growth hormone therapy in improving endocrine outcomes in SGA and preterm populations, indicating the need for tailored strategies.

Key Points

  • GH therapy significantly improved linear growth by +2.0 to +2.5 SDS, enhancing health outcomes in SGA children.
  • Endocrine abnormalities were prevalent, highlighting the need for early treatment to prevent complications.
  • Structured review utilized 28 studies and synthesized results into clear figures, providing insights into GH therapy efficacy.
  • Personalized GH therapy considering individual risk factors shows promise for optimizing treatment and outcomes.

Cite This Study

Soliman et al. (2025) studied this question.

synapsesocial.com/papers/68c1bd4254b1d3bfb60eeaebhttps://doi.org/10.30574/gscarr.2025.24.1.0206
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Metabolic and Growth Outcome of Two-year Growth Hormone Treatment in Children Born Small for Gestational Age: A Retrospective Study2024
  2. 2Growth hormone therapy in children born small for gestational age with persistent short stature (SGA-SS): Lessons learned from real-world international databases and directions for future research2026
  3. 3Early Initiation of rhGH Therapy Significantly Improves Height Gain and Reduces the Gap to Target Height in Children Born Small for Gestational Age: A Multicenter Retrospective Study2026
  4. 4From Replacement to Tailoring: Evolving Concepts in the Therapy for Short Stature2025
  5. 5Editorial: Growth Hormone Treatment of “Idiopathic Short Stature”: Not So Fast2004 · 23 citations