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September 10, 2025Open Access

When Genes Wear Marks: Epigenomic Modulation in the Development and Progression of Obesity

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Authors

ANAlexandra F. NikolaevaМНМ. В. НемцоваAPAnna V. Pustovalova

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Overview

This review highlights epigenetic mechanisms impacting obesity, suggesting targeted strategies and biomarkers.

Key Points

  • Epigenetic alterations play a critical role in obesity progression, influencing various metabolic pathways.
  • Key epigenetic modifications include DNA methylation, microRNA dysregulation, and chromatin remodeling.
  • The review focuses on tissue-specific alterations in adipose tissue, hepatocytes, and blood cells.
  • Understanding these mechanisms may lead to innovative diagnostic and therapeutic interventions for obesity.

Cite This Study

Nikolaeva et al. (2025) studied this question.

synapsesocial.com/papers/68c1c31b54b1d3bfb60f09b9https://doi.org/10.20944/preprints202508.0571.v1
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  1. 1When Genes Wear Marks: Epigenomic Modulation in the Development and Progression of Obesity2025 · 1 citations
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  4. 4Epigenetics and Childhood Obesity: DNA Methylation Coordinates Environment and Gene Regulation2026
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