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September 10, 2025Journal of Agricultural and Food Chemistry

Discovery of Novel Pyrazole-4-carboxamide Derivatives with Thioether Moiety as Potential SDHI Agents for Crop Protection

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Authors

BLBo LuoYWYanbing WuMCMinna Cao

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Overview

Assessment of new SDHI agents improved antifungal activity in plants, indicating potential for agricultural use.

Key Points

  • Compound 8e emerged as a leading SDHI candidate, demonstrating remarkable antifungal potency against Rhizoctonia solani.
  • The antifungal activity of compound 8e was significantly superior compared to boscalid and comparable to fluxapyroxad.
  • Molecular docking and SEM analysis confirmed the effective antifungal mechanism of compound 8e on pathogenic fungi.
  • These findings support the potential of compound 8e for crop protection, particularly for rice and oilseed rape.

Cite This Study

Luo et al. (2025) studied this question.

synapsesocial.com/papers/68c1d23a54b1d3bfb60f8027https://doi.org/10.1021/acs.jafc.5c03082
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