Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 12, 2025Journal of HematopathologyOpen Access

Validation of clinicopathologic features of a genetic myelodysplastic syndrome classification in an independent cohort

View Full Paper
Ask AI
Bookmark
Share

Authors

PPPranav Pramod PatwardhanRARamzi AmriVBVandana Baloda

Discussion

Loading...

Member takes

Overview

Analysis validates molecular groups and survival associations in myelodysplastic syndromes, suggesting clinical significance.

Key Points

  • The study verifies the MDS-IWG molecular classification's applicability in clinical practice and prognosis.
  • Monocytosis was significantly associated with the bi-TET2 group, indicating its importance in risk assessment.
  • The MDS-IWG classification highlights distinct survival differences, especially within the TP53-complex group.
  • Blast counts were shown to influence prognosis differently across low-risk and high-risk molecular groups.

Cite This Study

Patwardhan et al. (2025) studied this question.

synapsesocial.com/papers/68d44c4d31b076d99fa55f55https://doi.org/10.1007/s12308-025-00658-2
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinico‐genetic and prognostic analyses of 716 patients with primary myelodysplastic syndrome and myelodysplastic syndrome/acute myeloid leukemia based on the 2022 International Consensus Classification2023 · 15 citations
  2. 2Molecular subclusters across the continuum of myelodysplastic neoplasms and acute myeloid leukaemia define distinct clinical entities2025
  3. 3Distinctive Molecular Risk Factors Between <scp>MDS</scp> and <scp>MDS</scp> / <scp>AML</scp> Defined by <scp>ICC</scp>2026 · 1 citations
  4. 4Prognostic implications of genetic and transcriptomic abnormalities in MDS according to IPSS-R, IPSS-M, and the International Consensus Classification2026 · 1 citations
  5. 5Robotic Assisted Bronchoscopy: An Institutional Correlation Between Cytopathology and Surgical Resection Diagnoses2024