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September 16, 2025MedicinaOpen Access

Retrospective Analysis of Therapeutic Modalities in Prosthetic Heart Valve Thrombosis: A 15-Year Single-Center Experience

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Authors

AUA UzunselviSYSerkan YükselAnkara UniversityMUMuhammet UyanikState Hospital

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Implication

Retrospective study assesses survival rates and treatment effectiveness in prosthetic valve thrombosis patients, highlighting key predictors.

Key Points

  • Treatment using low-dose t-PA resulted in the lowest mortality rate of 7.4%, outperforming other modalities.
  • Overall treatment success for prosthetic valve thrombosis was 60.5%, with significant variance among treatment types.
  • Patients with NYHA class III-IV experienced a mortality rate of 68.2%, drastically higher than those in class I-II.
  • Multivariate analysis confirmed that NYHA III-IV is a strong predictor of mortality, elevating risks significantly.

Cite This Study

Uzunselvi et al. (2025) studied this question.

synapsesocial.com/papers/68d4565431b076d99fa5ae53https://doi.org/10.3390/medicina61091629
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