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September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Aberrant Intra-Cerebellar and Cerebro-Cerebellar Functional Connectivity in Early Schizophrenia Spectrum Disorder

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Authors

ZYZakia Ben YoussNew York UniversityYSYu Veronica SuiNew York UniversityRFRyn FlahertyCentre National de la Recherche Scientifique

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Overview

Study reveals altered functional connectivity in the cerebellum and its link to cognitive impairment in schizophrenia spectrum disorder.

Key Points

  • Significant reductions in intra-cerebellar functional connectivity were found in key cerebellar regions.
  • Cerebro-cerebellar functional connectivity was aberrant in patients with early schizophrenia spectrum disorder compared to controls.
  • Resting-state fMRI and seed-based connectivity analyses were utilized to assess functional connectivity in this research.
  • Highlighting cerebellar abnormalities may improve the understanding of cognitive impairments in schizophrenia spectrum disorder.

Cite This Study

Youss et al. (2025) studied this question.

synapsesocial.com/papers/68d4597031b076d99fa5c3fehttps://doi.org/10.58530/2025/2484
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  1. 1Functional dysconnectivity in Schizophrenia and Bipolar Disorder: associations with cognitive impairment2025
  2. 2Cerebellar dysconnectivity in schizophrenia and bipolar disorder is associated with cognitive and clinical variables2024 · 7 citations
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  4. 4Functional Connectivity of Language-Related Cerebellar Regions Is Reduced in Schizophrenia Patients2024 · 2 citations
  5. 5Weaker Cerebellocortical Connectivity Within Sensorimotor and Executive Networks in Schizophrenia Compared to Healthy Controls: Relationships with Processing Speed2020 · 21 citations