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Brain Structural and Functional Connectivity Alterations in Heart Failure Patients

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Prospective study shows cognitive deficits in heart failure patients relate to brain alterations and connectivity changes.

Heart failure patients exhibited significant atrophy in brain regions associated with memory and executive functions, indicating serious impacts on cognition.
The study found enhanced functional connectivity yet reduced cortical thickness in heart failure patients, highlighting significant structural and functional brain changes.
This observational study analyzed brain MRI scans alongside cognitive assessments in heart failure patients compared to controls, emphasizing the effects of heart failure etiology.
Understanding these neurological changes is crucial, as they point to potential interventions for managing cognitive decline in heart failure patients.

Pan et al. (2025) studied this question.

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