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September 17, 2025Iranian Journal of Public HealthOpen Access

ACTN3 R577X and ACE I/D Polymorphisms and Sports Performance: A Systematic Review

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Authors

SKSedat Kahya

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Overview

Systematic review highlights the connection between actn3 r577x, ace polymorphisms, and athletic performance.

Key Points

  • Significant differences in sports performance related to actn3 r577x and ace polymorphisms were noted in 5 out of 9 studies.
  • A total of 224 studies were analyzed for the relationship between these polymorphisms and sports performance.
  • The review included data from 756 cases, 2,191 controls, and 178 individuals from various studies.
  • Risk analysis conducted identified 3 articles as having a moderate, serious, and critical risk of bias.

Cite This Study

Sedat Kahya (2025) studied this question.

synapsesocial.com/papers/68d4604031b076d99fa5f387https://doi.org/10.18502/ijph.v54i8.19571
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Association of Sport Performance with ACE and ACTN3 Genetic Polymorphisms: A Systematic Review and Meta-Analysis2013 · 310 citations
  2. 2The association of the <i>ACTN3</i> R577X and <i>ACE</i> I/D polymorphisms with athlete status in football: a systematic review and meta-analysis2020 · 53 citations
  3. 3Association between ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M268T) polymorphisms and performance phenotypes in Brazilian swimmers2024 · 7 citations
  4. 4Ace I/d And Actn3 R577x Polymorphism In Elite Athletes2005 · 4 citations
  5. 5Association between <i>ACE</i> and <i>ACTN3</i> genes polymorphisms and athletic performance in elite and sub-elite Chinese youth male football players2023 · 17 citations