Characterization of copper complexes reveals cytotoxic effects on breast cancer and normal cells, suggesting therapeutic potential.
Breast cancer poses a serious threat to women's health. In this study, we obtained two different copper-based complexes (Ⅰ) and (Ⅱ) in a reaction system, and characterized their crystal structures using X-ray single crystal diffraction technology. Additionally, the cytotoxic effects of these two copper complexes on two breast cancer cell lines (MCF-7 and MDA-MB-231) ,non-cancerous human umbilical vein endothelial cells (HUVECs) and normal human liver cells (LO2) were evaluated using the MTT assay. The obtained results provided certain theoretical and practical foundations for the development of potential anti-cancer drugs.
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Lin et al. (2025) studied this question.
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