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September 20, 2025CureusOpen Access

Early Massive Left Atrial Thrombosis Following Mitral Bioprosthetic Valve Replacement Due to Suboptimal Anticoagulation: A Case Report

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Authors

WLWanli LiuZLZhongkui LiCFChao Feng

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Overview

Case report highlights early left atrial thrombus after bioprosthetic valve replacement, indicating critical anticoagulation monitoring.

Key Points

  • Complete resolution of the left atrial thrombus occurred after three months, showing effective treatment with anticoagulation.
  • A giant thrombus measuring 79 × 55 × 45 mm developed, with a subtherapeutic INR of 1.18 observed at follow-up.
  • The patient, a 61-year-old woman, underwent mitral valve replacement alongside tricuspid ring annuloplasty and left atrial plication.
  • Strict monitoring of INR is crucial for high-risk patients, emphasizing warfarin's effectiveness for left atrial thrombi.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68d46ab431b076d99fa67d05https://doi.org/10.7759/cureus.92572
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early Degeneration of a Bioprosthetic Mitral Valve Complicated by a Large Left Atrial Thrombus2011 · 2 citations
  2. 2Early Postoperative Immunothrombosis of Bioprosthetic Mitral Valve and Left Atrium: A Case Report2022 · 5 citations
  3. 3Left atrial Thrombus formation after discontinuation of anticoagulation in patient with severe bioprosthetic mitral stenosis2023 · 2 citations
  4. 4Management of giant left atrial thrombus late after transcatheter mitral valve-in-ring replacement using a transcatheter aortic valve: a case report2024 · 2 citations
  5. 5Surgical Treatment of Early Acute Thrombosis of Mechanical Mitral Prosthesis2010