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September 23, 2025Deleted JournalOpen Access

Enhanced Hyaluronic Acid Production in Streptococcus equi subsp. Streptococcuszooepidemicus Through Strain Mutagenesis and Optimized Purification

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This research enhances hyaluronic acid yield and reduces enzymatic degradation in Streptococcus equi, indicating improved purification strategies.

HA yield increased by 85.7% from the wild type to the selected mutant strain, demonstrating improved production efficiency.
The mutant strain maintained stable characteristics over 15 generations, proving the effectiveness of mutagenesis in optimizing HA production.
An efficient purification process reduced organic solvent use by 25-fold compared to conventional methods, highlighting environmental benefits.
The average molecular weight of HA increased from 6.7 × 104 Da to 1.2 × 105 Da, indicating enhanced product quality.

Hedayat et al. (2025) studied this question.

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September 23, 2025Deleted JournalOpen Access

View Full Paper

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Authors

This research enhances hyaluronic acid yield and reduces enzymatic degradation in Streptococcus equi, indicating improved purification strategies.

HA yield increased by 85.7% from the wild type to the selected mutant strain, demonstrating improved production efficiency.
The mutant strain maintained stable characteristics over 15 generations, proving the effectiveness of mutagenesis in optimizing HA production.
An efficient purification process reduced organic solvent use by 25-fold compared to conventional methods, highlighting environmental benefits.
The average molecular weight of HA increased from 6.7 × 104 Da to 1.2 × 105 Da, indicating enhanced product quality.

Hedayat et al. (2025) studied this question.

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