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September 23, 2025Brain and BehaviorOpen Access

A Meta‐Analysis of Multidimensional Cognitive Functions Changes in Different Intensities of High‐Altitude Hypoxia

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Authors

JYJiang YanKCKeda CaiLZLingling Zhu

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Overview

Meta-analysis evaluates high-altitude hypoxia's effects on cognitive functions, indicating significant impairments across varied cognitive domains.

Key Points

  • High-altitude hypoxia significantly impairs overall cognitive function, particularly affecting long-term memory.
  • Substantial cognitive impairment occurs at altitudes above 2500 m, with exposure duration impacting severity.
  • Meta-analysis aggregated data from 59 studies, analyzing 739 effect sizes using multilevel modeling.
  • Findings suggest a need for tailored interventions addressing acclimatization processes based on cognitive domain sensitivity.

Cite This Study

Yan et al. (2025) studied this question.

synapsesocial.com/papers/68d4725d31b076d99fa6b400https://doi.org/10.1002/brb3.70883
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  5. 5Higher Prevalence of Cognitive Impairment in Residents of High-Altitude Regions2026