Why the study?
Does acute high-altitude exposure impair working memory and alter cerebral hemodynamic response in human subjects?
Population
Subjects performing working memory exercises
Comparison
Acute high-altitude exposure in large simulated… vs Normal oxygen conditions (normoxia)
Design
Other
Key result
Acute high-altitude exposure decreased accuracy and increased response time in complex working memory tasks, accompanied by abnormal hemodynamic responses in the dorsolateral prefrontal cortex.
Authors
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Supports caution for high-stakes decisions at altitude; hypothesis-generating for dorsolateral prefrontal cortex hemodynamics in larger studies.
Does acute high-altitude exposure impair working memory and alter cerebral hemodynamic response in human subjects?
Acute high-altitude exposure impairs complex cognitive functions and alters hemodynamic responses in the dorsolateral prefrontal cortex.
Wang et al. (2022) studied Acute high-altitude exposure. Acute high-altitude exposure (simulated hypobaric hypoxia) vs. Normal oxygen conditions was evaluated on Cerebral hemodynamic response and working memory. Acute high-altitude exposure decreased accuracy and increased response time in complex working memory tasks, accompanied by abnormal hemodynamic responses in the dorsolateral prefrontal cortex.
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