Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 30, 2025Sahel Journal of Veterinary SciencesOpen Access

Polyalthia Longifolia Ameliorates Isoprenaline-Induced Myocardial Toxicity via Markers of Oxidative Stress and Inflammation in Wistar Rats

View Full Paper
Ask AI
Bookmark
Share

Authors

ESEkundayo Stephen SamuelTOT. OjetolaOAOlumuyiwa Abiola Adejumobi

Discussion

Loading...

Member takes

Overview

Observational analysis shows Polyalthia longifolia reduces oxidative stress and inflammation in myocardial infarction, suggesting a potential healing role.

Key Points

  • Polyalthia longifolia significantly mitigated isoprenaline-induced myocardial toxicity, improving heart function and stability.
  • Treatment with PL and vitamin C reversed the oxidative stress and inflammation caused by isoprenaline, highlighting their protective effects.
  • Wistar rats treated with PL showed reduced inflammatory cells and heart tissue damage, compared to those only given isoprenaline.
  • The study underscored the significant potential of phenol-rich Polyalthia longifolia as a natural therapeutic agent for myocardial injury.

Cite This Study

Samuel et al. (2025) studied this question.

synapsesocial.com/papers/68dc262a8a7d58c25ebb35edhttps://doi.org/10.54058/vkxwp365
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Phloroglucinol averts isoprenaline hydrochloride induced myocardial infarction in rats2019 · 18 citations
  2. 2Attenuation of isoprenaline-induced myocardial infarction by Rheum turkestanicum2022 · 39 citations
  3. 3Protective Effect of Prunetin on Isoproterenol-Induced Myocardial Infarction in Wistar Rats via Biochemical Characterization2024 · 3 citations
  4. 4Effect of folic acid on isoprenaline-induced myocardial injury in rats2024 · 9 citations
  5. 5(—)-Epigallocatechin gallate (EGCG) prevents isoprenaline-induced cardiac toxicity by stabilizing cardiac marker enzymes and membrane-bound ATPases2007 · 34 citations