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This is a Literature Review study.

October 1, 2025Dubai Medical JournalOpen Access

Plant-based Phytoconstituents/Bioactive Compounds as Preventive and Therapeutic Agents for Their Nephrolithiasis/Anti-nephrolithiasis Properties

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This review highlights the impact of phytoconstituents and bioactive compounds on nephrolithiasis, suggesting alternative management strategies.

Plant-derived bioactive compounds show promising anti-nephrolithiasis effects, inhibiting stone formation and aiding in treatment.
Specific compounds from Tribulus terrestris, Phyllanthus niruri, and Citrus limon can obstruct calcium oxalate aggregation, a key factor in kidney stones.
The study emphasizes the antioxidant and anti-inflammatory properties of these compounds that help alleviate kidney issues.
Further clinical trials are essential to confirm the safety and efficacy of phytotherapeutic agents in managing nephrolithiasis.

Prabhu et al. (2025) studied this question.

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This review highlights the impact of phytoconstituents and bioactive compounds on nephrolithiasis, suggesting alternative management strategies.