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October 1, 2025

Association Between Preoperative Psychological Symptoms and Chronic Postsurgical Pain in Older Patients Undergoing off-Pump Coronary Artery Bypass Grafting: Mediation Analysis of Acute Pain.

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Authors

SCSichen CuiHebei Medical UniversitySWShizhao WangChinese Academy of SciencesLDLichao DiHebei Medical University

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Overview

Logistic regression links preoperative anxiety and depression to chronic postsurgical pain, suggesting acute pain mediates this relationship.

Key Points

  • Chronic postsurgical pain affects 37.8% of older patients following off-pump CABG, with higher rates of anxiety and depression observed.
  • Preoperative anxiety significantly predicts chronic postsurgical pain with an odds ratio of 3.64, highlighting the importance of mental health.
  • The study employed logistic regression and mediation analysis to assess the connection between psychological symptoms and chronic pain.
  • Improving psychological health and managing acute pain may reduce the risk of chronic pain in older CABG patients, which is crucial.

Cite This Study

Cui et al. (2025) studied this question.

synapsesocial.com/papers/68dd89e6fe798ba2fc497fa0https://doi.org/10.2147/jpr.s537096
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The long‐term incidence of chronic post‐surgical pain after coronary artery bypass surgery – A prospective observational study2023 · 6 citations
  2. 2Chronic Postsurgical Pain-Induced Postoperative Anxiety Risk2025
  3. 3Pre-surgical depression and anxiety and recovery following coronary artery bypass graft surgery2016 · 47 citations
  4. 4Postoperative chronic pain incidence and etiology in coronary artery bypass graft surgery: a prospective study2021 · 1 citations
  5. 5The preoperative risk factors of chronic postsurgical pain: a retrospective cohort study in the UK Biobank2025