Anti-Inflammatory and Antioxidant Action of Astaxanthin and Its Applications in the Treatment of Muscle Health: A Systematic Review

Background: Muscle health is essential for overall physical function and quality of life (QOL). Astaxanthin (AST), a potent antioxidant carotenoid, has shown promise for improving muscle function and reducing inflammation. Objective: This systematic review aims at evaluation of anti-inflammatory and antioxidant effects of AST supplementation on muscle health. Methods: A comprehensive search was conducted across electronic databases, following PRISMA guidelines from January 2005 to December 2023, to identify uses of AST in Muscle pain and 10 studies fulfilling inclusion criteria were selected. Results: Four out of ten studies focused on the antioxidant and anti-inflammatory effects of AST supplementation on muscle strength, while others focused on the muscle soreness. Conclusion: AST supplementation holds as a promising adjunctive therapy for promoting muscle health and reducing inflammation.