Supplementary Figure S3 from Molecular Characterization of Residual Muscle-Invasive Bladder Cancer Identifies a Scar-Like Transcriptomic Profile with Favorable Prognosis after Neoadjuvant Therapy

Key Points

• Distinct biological clusters identified from gene expression profiling, impacting prognosis significantly.
• Analysis of gene markers like KRT5 and CD44 reveals potential for improved outcomes after neoadjuvant therapy.
• Method derived from gene expression scores in cystectomy samples, highlighting the role of transcripts in treatment response.
• Findings suggest transcriptomic profiles may guide future treatment approaches and patient management in bladder cancer.