Supplementary Figure S6 from Molecular Characterization of Residual Muscle-Invasive Bladder Cancer Identifies a Scar-Like Transcriptomic Profile with Favorable Prognosis after Neoadjuvant Therapy

Joep J. de Jong; Moritz J. Reike; Yair Lotan; Roland Seiler; Elai Davicioni; Andrea Necchi; Thomas Powles; Peter C. Black; Bernadett Szabados; Ewan A. Gibb

doi:10.1158/1078-0432.30255727

October 1, 2025Open Access

Supplementary Figure S6 from Molecular Characterization of Residual Muscle-Invasive Bladder Cancer Identifies a Scar-Like Transcriptomic Profile with Favorable Prognosis after Neoadjuvant Therapy

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Key Points

Kaplan-Meier curves indicate disease free survival outcomes for stroma-rich tumors, showing no significant difference.
Consensus stroma-rich tumors display a Log-Rank P value of 0.27, indicating a neutral trend in survival.
This observational analysis focuses on outcomes within the post-neoadjuvant therapy cohort.
Results highlight the need for further validation across diverse populations to confirm prognostic significance.

Implication

Analysis reveals disease free survival trends in stroma-rich tumors post-neoadjuvant therapy, suggesting prognostic insights.

Abstract

Figure S6. Kapplan-Meier curves comparing disease free survival outcomes for Consensus stroma-rich tumors within the post-NAC cohort (Log-Rank P = 0.27).

Discussion

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Cite This Study

Jong et al. (2025) studied this question.

synapsesocial.com/papers/68e040f7a99c246f578b3d6f https://doi.org/10.1158/1078-0432.30255727

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Supplementary Figure S6 from Molecular Characterization of Residual Muscle-Invasive Bladder Cancer Identifies a Scar-Like Transcriptomic Profile with Favorable Prognosis after Neoadjuvant Therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure S6 from Molecular Characterization of Residual Muscle-Invasive Bladder Cancer Identifies a Scar-Like Transcriptomic Profile with Favorable Prognosis after Neoadjuvant Therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

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