Supplementary Figure S3 from Genomic and Epigenomic ctDNA Profiling in Liquid Biopsies from Heavily Pretreated Patients with DNA Damage Response–Deficient Tumors

This is a Quantitative Study study (also classified as: Cohort Study).

Key Points

Patients with dna damage response–deficient tumors showed positive results in ctDNA-based enrollment.
Key findings include successful detection of specific allelic statuses in liquid biopsies via ctDNA analysis.
This research utilized genomic and epigenomic profiling techniques to understand tumor characteristics.
Liquid biopsies may represent a less invasive alternative for analyzing tumor genetics in heavily pretreated patients.

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Research shows ctDNA-based enrollment PV detection and allelic status in patients with tumors, indicating the utility of liquid biopsies.

ctDNA-based enrollment PV detection and allelic status calls.

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Silverman et al. (2025) studied this question.

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