Supplementary Figure S4 from Genomic and Epigenomic ctDNA Profiling in Liquid Biopsies from Heavily Pretreated Patients with DNA Damage Response–Deficient Tumors

This is a Quantitative Study study.

Key Points

cHRD scores were analyzed in the context of tumor type and genotype, showing significant patterns.
The study focused on ctDNA derived from liquid biopsies to evaluate DNA damage response deficiencies.
Results from this profiling may guide treatment decisions in patients with resistant tumor types.
Understanding the genomic and epigenomic features can improve therapeutic strategies for these patients.

Analysis reveals cHRD scores in heavily pretreated tumor patients, indicating genetic implications in therapy outcomes.

cHRD scores based on tumor type, genotype and tumor or ctDNA-derived allelic status.

No takes yet. Share an insight, caveat, or question.

Silverman et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Share