(A) DEGs in BRCA2null vs BRCA1null 4T1 mouse breast cancer cell line reported as log fold-change (logFC); red bars are upregulated and blue bars are downregulated; (B) Perturbation analysis of Wnt signaling pathway comparing BRCA2null vs BRCA1null 4T1 mouse breast cancer cell line; red genes are predicted to be upregulated and blue genes are predicted to be downregulated.
No takes yet. Share an insight, caveat, or question.
Chehade et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: