Endothelial Dysfunction Using Flow-Mediated Dilatation Among Individuals with Pre-Impaired Glucose Tolerance (Pre-IGT)*

Pre-impaired glucose tolerance (pre-IGT) is a prediabetes stage characterized by normoglycemia and compensatory hyperinsulinemia due to insulin resistance. Hyperinsulinemia increases cardiovascular disease (CVD) risk, especially, endothelial dysfunction (ED). However, there is paucity of studies on ED with hyperinsulinemia alone, particularly in individuals with pre-IGT. This study aimed to determine the presence of ED using brachial artery flowmediated dilatation (FMD) among adult participants with pre-IGT and its correlation with insulin levels and other related clinical parameters.