September 9, 2024Dementia and Geriatric Cognitive Disorders ExtraOpen Access

Characteristics of Alzheimer's disease and mild cognitive impairment influenced by the time of onset

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Preserved hippocampal volume and higher recall scores characterize early-onset mild cognitive impairment, whereas late-onset cases exhibit marked medial temporal atrophy.
Assessment using 1.5 Tesla magnetic resonance imaging and Mini-Mental State Examination evaluated regional gray matter volumes across five diagnostic groups.
Findings highlight that differing neuropsychological profiles between early- and late-onset alzheimers disease already manifest during intermediate impairment stages.

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Implication

Comparative analysis reveals preserved hippocampal volume in early-onset impairment, indicating distinct neurodegenerative patterns between early and late onset.

Cite This Study

Sato et al. (2024) studied this question.

synapsesocial.com/papers/68e590e0b6db64358752be40 https://doi.org/10.1159/000541092

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Implication

Comparative analysis reveals preserved hippocampal volume in early-onset impairment, indicating distinct neurodegenerative patterns between early and late onset.

Characteristics of Alzheimer's disease and mild cognitive impairment influenced by the time of onset

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Discussion

Implication

Cite This Study

Characteristics of Alzheimer's disease and mild cognitive impairment influenced by the time of onset

Key Points

Discussion

Implication

Cite This Study

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