Validation of Non-Invasive Relative Pressure Mapping by 4D Flow MRI in Aortic Dissection

False lumen (FL) growth rate in type B aortic dissection (TBAD) is correlated with FL pressurization. 4D flow MRI allows for quantitative assessment of three-dimensional flow, including spatial mapping of relative pressure. Despite its promise, 4D flow relative pressure mapping has not yet been validated in a TBAD-specific context. Here, we validate a state-of-the-art proposed Stokes Estimator (STE) of relative pressure against catheter measurements using three physiologically accurate TBAD flow phantoms and subsequently analyze the method’s sensitivity to image noise. STE pressure estimates closely matched catheter data and were robust to noise, indicating STE’s potential for TBAD treatment planning.