Key result
4D flow MRI reveals elevated true lumen reverse flow and kinetic energy after type A dissection repair.
Why the study?
Systematic evaluation of complex flow in the true and false lumens is needed to better understand which patients with chronic descending aortic dissection are predisposed to complications.
Can 4D flow MRI-derived quantitative hemodynamic maps detect regional flow differences in patients with chronic descending aortic dissection compared to controls?
Population
20 chronic descending aortic dissection patients and 21 age-matched controls
Comparison
Repaired type A AD vs medically managed type B AD vs controls
Design
Retrospective study
Authors
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4D flow MRI may detect hemodynamic abnormalities after aortic repair; leaves open its value for risk stratification pending prospective data.
Observational (n=41)
Can 4D flow MRI-derived quantitative hemodynamic maps detect regional flow differences in patients with chronic descending aortic dissection compared to controls?
4D flow MRI-derived parametric hemodynamic maps can quantify regional flow differences in true and false lumens of patients with chronic descending aortic dissection, potentially aiding in risk stratification.
Jarvis et al. (2019) conducted an observational in Chronic descending aortic dissection (n=41). 4D flow MRI vs. Age-matched controls was evaluated on True lumen and false lumen flow characteristics (forward flow, reverse flow, flow stasis, and kinetic energy). 4D flow MRI revealed that patients with repaired type A aortic dissection had significantly elevated true lumen reverse flow (P=0.004) and kinetic energy (P=0.0002) compared to controls.
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